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New Insight into Atherosclerosis in Hemodialysis Patients: Overexpression of Scavenger Receptor and Macrophage Colony-Stimulating Factor Genes.

Nephron extra

Nishida M, Ando M, Iwamoto Y, Tsuchiya K, Nitta K.
PMID: 27721822
Nephron Extra. 2016 Aug 27;6(2):22-30. doi: 10.1159/000448486. eCollection 2016.

BACKGROUND: Scavenger receptors (SRs) play a pivotal role in atherogenesis. The mechanism of atherosclerosis, which is specific to hemodialysis (HD) patients, was studied on the basis of SR gene expressions.METHODS: The gene expressions of SR type A (SR-A) and...

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Nishida M, Ando M, Iwamoto Y, et al. New Insight into Atherosclerosis in Hemodialysis Patients: Overexpression of Scavenger Receptor and Macrophage Colony-Stimulating Factor Genes. Nephron Extra. 2016;6(2):22-30doi: 10.1159/000448486.
Nishida, M., Ando, M., Iwamoto, Y., Tsuchiya, K., & Nitta, K. (2016). New Insight into Atherosclerosis in Hemodialysis Patients: Overexpression of Scavenger Receptor and Macrophage Colony-Stimulating Factor Genes. Nephron extra, 6(2), 22-30. https://doi.org/10.1159/000448486
Nishida, Miki, et al. "New Insight into Atherosclerosis in Hemodialysis Patients: Overexpression of Scavenger Receptor and Macrophage Colony-Stimulating Factor Genes." Nephron extra vol. 6,2 (2016): 22-30. doi: https://doi.org/10.1159/000448486
Nishida M, Ando M, Iwamoto Y, Tsuchiya K, Nitta K. New Insight into Atherosclerosis in Hemodialysis Patients: Overexpression of Scavenger Receptor and Macrophage Colony-Stimulating Factor Genes. Nephron Extra. 2016 Aug 27;6(2):22-30. doi: 10.1159/000448486. eCollection 2016. PMID: 27721822; PMCID: PMC5040927.
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Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study.

Nephron extra

Hara T, Mukai H, Nakashima T, Sagara R, Furusho M, Miura S, Toyonaga J, Sugawara K, Takeda K.
PMID: 26648974
Nephron Extra. 2015 Oct 28;5(3):79-86. doi: 10.1159/000441154. eCollection 2015.

BACKGROUND: Factors contributing to erythropoietin (EPO) hyporesponsiveness in patients on long-term continuous ambulatory peritoneal dialysis are not well understood. Therefore, we investigated the factors contributing to EPO hyporesponsiveness using the EPO resistance index (ERI).METHODS: A total of 14 patients...

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Hara T, Mukai H, Nakashima T, et al. Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study. Nephron Extra. 2015;5(3):79-86doi: 10.1159/000441154.
Hara, T., Mukai, H., Nakashima, T., Sagara, R., Furusho, M., Miura, S., Toyonaga, J., Sugawara, K., & Takeda, K. (2015). Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study. Nephron extra, 5(3), 79-86. https://doi.org/10.1159/000441154
Hara, Takashi, et al. "Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study." Nephron extra vol. 5,3 (2015): 79-86. doi: https://doi.org/10.1159/000441154
Hara T, Mukai H, Nakashima T, Sagara R, Furusho M, Miura S, Toyonaga J, Sugawara K, Takeda K. Factors Contributing to Erythropoietin Hyporesponsiveness in Patients on Long-Term Continuous Ambulatory Peritoneal Dialysis: A Cross-Sectional Study. Nephron Extra. 2015 Oct 28;5(3):79-86. doi: 10.1159/000441154. eCollection 2015. PMID: 26648974; PMCID: PMC4662269.
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Regulation of Hepcidin-25 by Short- and Long-Acting rhEPO May Be Dependent on Ferritin and Predict the Response to rhEPO in Hemodialysis Patients.

Nephron extra

Takasawa K, Tomosugi N, Takaeda C, Maeda T, Ueda N.
PMID: 24847351
Nephron Extra. 2014 Apr 16;4(1):55-63. doi: 10.1159/000362212. eCollection 2014 Jan.

BACKGROUND/AIMS: We examined whether regulation of hepcidin-25 by short- or long-acting recombinant human erythropoietin (rhEPO) is dependent on ferritin and predicts the response to rhEPO in hemodialysis (HD) patients.METHODS: Two studies with rhEPO were performed in 9 HD patients...

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Takasawa K, Tomosugi N, Takaeda C, et al. Regulation of Hepcidin-25 by Short- and Long-Acting rhEPO May Be Dependent on Ferritin and Predict the Response to rhEPO in Hemodialysis Patients. Nephron Extra. 2014;4(1):55-63doi: 10.1159/000362212.
Takasawa, K., Tomosugi, N., Takaeda, C., Maeda, T., & Ueda, N. (2014). Regulation of Hepcidin-25 by Short- and Long-Acting rhEPO May Be Dependent on Ferritin and Predict the Response to rhEPO in Hemodialysis Patients. Nephron extra, 4(1), 55-63. https://doi.org/10.1159/000362212
Takasawa, Kazuya, et al. "Regulation of Hepcidin-25 by Short- and Long-Acting rhEPO May Be Dependent on Ferritin and Predict the Response to rhEPO in Hemodialysis Patients." Nephron extra vol. 4,1 (2014): 55-63. doi: https://doi.org/10.1159/000362212
Takasawa K, Tomosugi N, Takaeda C, Maeda T, Ueda N. Regulation of Hepcidin-25 by Short- and Long-Acting rhEPO May Be Dependent on Ferritin and Predict the Response to rhEPO in Hemodialysis Patients. Nephron Extra. 2014 Apr 16;4(1):55-63. doi: 10.1159/000362212. eCollection 2014 Jan. PMID: 24847351; PMCID: PMC4024510.
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Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery.

Nephron extra

Koukoulaki M, Spyropoulos C, Hondrogiannis P, Papachristou E, Mitsi E, Kalfarentzos F, Goumenos DS.
PMID: 24348505
Nephron Extra. 2013 Oct 31;3(1):101-105. doi: 10.1159/000354892. eCollection 2013.

INTRODUCTION: Neutrophil gelatinase-associated lipocalin (NGAL) has been identified as a biomarker of acute kidney injury (AKI) that could contribute to early diagnosis and effective management of AKI. The purpose of this study was to evaluate NGAL as a predictive...

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Koukoulaki M, Spyropoulos C, Hondrogiannis P, et al. Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery. Nephron Extra. 2013;3(1):101-105doi: 10.1159/000354892.
Koukoulaki, M., Spyropoulos, C., Hondrogiannis, P., Papachristou, E., Mitsi, E., Kalfarentzos, F., & Goumenos, D. S. (2013). Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery. Nephron extra, 3(1), 101-105. https://doi.org/10.1159/000354892
Koukoulaki, Maria, et al. "Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery." Nephron extra vol. 3,1 (2013): 101-105. doi: https://doi.org/10.1159/000354892
Koukoulaki M, Spyropoulos C, Hondrogiannis P, Papachristou E, Mitsi E, Kalfarentzos F, Goumenos DS. Neutrophil Gelatinase-Associated Lipocalin as a Biomarker of Acute Kidney Injury in Patients with Morbid Obesity Who Underwent Bariatric Surgery. Nephron Extra. 2013 Oct 31;3(1):101-105. doi: 10.1159/000354892. eCollection 2013. PMID: 24348505; PMCID: PMC3843911.
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Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease.

Nephron extra

Togawa A, Uyama S, Takanohashi S, Shimasaki M, Miyaji T, Endo H, Fujigaki Y.
PMID: 24348507
Nephron Extra. 2013 Nov 14;3(1):113-117. doi: 10.1159/000356461. eCollection 2013.

BACKGROUND: Metabolic acidosis is known to accelerate the progression of chronic kidney disease (CKD). However, whether undetermined anions as indicated by the adjusted anion gap (aAG) are associated with estimated glomerular filtration rate (eGFR) decline in patients with CKD...

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Togawa A, Uyama S, Takanohashi S, et al. Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease. Nephron Extra. 2013;3(1):113-117doi: 10.1159/000356461.
Togawa, A., Uyama, S., Takanohashi, S., Shimasaki, M., Miyaji, T., Endo, H., & Fujigaki, Y. (2013). Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease. Nephron extra, 3(1), 113-117. https://doi.org/10.1159/000356461
Togawa, Akashi, et al. "Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease." Nephron extra vol. 3,1 (2013): 113-117. doi: https://doi.org/10.1159/000356461
Togawa A, Uyama S, Takanohashi S, Shimasaki M, Miyaji T, Endo H, Fujigaki Y. Adjusted Anion Gap Is Associated with Glomerular Filtration Rate Decline in Chronic Kidney Disease. Nephron Extra. 2013 Nov 14;3(1):113-117. doi: 10.1159/000356461. eCollection 2013. PMID: 24348507; PMCID: PMC3861847.
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A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation.

Nephron extra

Ito K, Ookawara S, Ueda Y, Miyazawa H, Yamada H, Goto S, Ishii H, Shindo M, Kitano T, Hirai K, Yoshida M, Kaku Y, Hoshino T, Nabata A, Mori H, Yoshida I, Kakei M, Morishita Y, Tabei K.
PMID: 26951636
Nephron Extra. 2015 Dec 19;5(3):100-10. doi: 10.1159/000442591. eCollection 2015.

UNLABELLED: A high cardiothoracic ratio (CTR) is indicative of a cardiac disorder. However, few reports have revealed an association between the CTR and mortality in patients starting hemodialysis (HD).METHODS: Patients with HD initiation (n = 387; mean age, 66.7...

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Ito K, Ookawara S, Ueda Y, et al. A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation. Nephron Extra. 2015;5(3):100-10doi: 10.1159/000442591.
Ito, K., Ookawara, S., Ueda, Y., Miyazawa, H., Yamada, H., Goto, S., Ishii, H., Shindo, M., Kitano, T., Hirai, K., Yoshida, M., Kaku, Y., Hoshino, T., Nabata, A., Mori, H., Yoshida, I., Kakei, M., Morishita, Y., & Tabei, K. (2015). A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation. Nephron extra, 5(3), 100-10. https://doi.org/10.1159/000442591
Ito, Kiyonori, et al. "A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation." Nephron extra vol. 5,3 (2015): 100-10. doi: https://doi.org/10.1159/000442591
Ito K, Ookawara S, Ueda Y, Miyazawa H, Yamada H, Goto S, Ishii H, Shindo M, Kitano T, Hirai K, Yoshida M, Kaku Y, Hoshino T, Nabata A, Mori H, Yoshida I, Kakei M, Morishita Y, Tabei K. A Higher Cardiothoracic Ratio Is Associated with 2-Year Mortality after Hemodialysis Initiation. Nephron Extra. 2015 Dec 19;5(3):100-10. doi: 10.1159/000442591. eCollection 2015. PMID: 26951636; PMCID: PMC4777940.
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Frequent hemodialysis fistula infectious complications.

Nephron extra

Lok CE, Sontrop JM, Faratro R, Chan CT, Zimmerman DL.
PMID: 25473405
Nephron Extra. 2014 Oct 14;4(3):159-67. doi: 10.1159/000366477. eCollection 2014 Sep.

BACKGROUND: Few studies have examined if infectious arteriovenous access complications vary with the cannulation technique and whether this is modified by dialysis frequency. We compared the infection rate between fistulas cannulated using buttonhole versus stepladder techniques for patients treated...

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Lok CE, Sontrop JM, Faratro R, et al. Frequent hemodialysis fistula infectious complications. Nephron Extra. 2014;4(3):159-67doi: 10.1159/000366477.
Lok, C. E., Sontrop, J. M., Faratro, R., Chan, C. T., & Zimmerman, D. L. (2014). Frequent hemodialysis fistula infectious complications. Nephron extra, 4(3), 159-67. https://doi.org/10.1159/000366477
Lok, Charmaine E, et al. "Frequent hemodialysis fistula infectious complications." Nephron extra vol. 4,3 (2014): 159-67. doi: https://doi.org/10.1159/000366477
Lok CE, Sontrop JM, Faratro R, Chan CT, Zimmerman DL. Frequent hemodialysis fistula infectious complications. Nephron Extra. 2014 Oct 14;4(3):159-67. doi: 10.1159/000366477. eCollection 2014 Sep. PMID: 25473405; PMCID: PMC4241642.
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Dialysis and quality of dialysate in southeast asian developing countries.

Nephron extra

Naramura T, Hyodo T, Kokubo K, Matsubara H, Wakai H, Nakajima F, Shibahara N, Yoshida K, Komaru Y, Kawanishi H, Kawamura A, Hidai H, Takesawa S.
PMID: 24926310
Nephron Extra. 2014 Apr 23;4(1):64-9. doi: 10.1159/000362454. eCollection 2014 Jan.

BACKGROUND: The number of dialysis patients has been increasing in Southeast Asia, but statistical data about these patients and on the quality of dialysates in Southeast Asian dialysis facilities are still imprecise. For this study, dialysis-related statistical data were...

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Naramura T, Hyodo T, Kokubo K, et al. Dialysis and quality of dialysate in southeast asian developing countries. Nephron Extra. 2014;4(1):64-9doi: 10.1159/000362454.
Naramura, T., Hyodo, T., Kokubo, K., Matsubara, H., Wakai, H., Nakajima, F., Shibahara, N., Yoshida, K., Komaru, Y., Kawanishi, H., Kawamura, A., Hidai, H., & Takesawa, S. (2014). Dialysis and quality of dialysate in southeast asian developing countries. Nephron extra, 4(1), 64-9. https://doi.org/10.1159/000362454
Naramura, Tomotaka, et al. "Dialysis and quality of dialysate in southeast asian developing countries." Nephron extra vol. 4,1 (2014): 64-9. doi: https://doi.org/10.1159/000362454
Naramura T, Hyodo T, Kokubo K, Matsubara H, Wakai H, Nakajima F, Shibahara N, Yoshida K, Komaru Y, Kawanishi H, Kawamura A, Hidai H, Takesawa S. Dialysis and quality of dialysate in southeast asian developing countries. Nephron Extra. 2014 Apr 23;4(1):64-9. doi: 10.1159/000362454. eCollection 2014 Jan. PMID: 24926310; PMCID: PMC4036132.
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Mesangioproliferative glomerulonephritis: a 30-year prognosis study.

Nephron extra

Axelsen M, Smith Pedersen R, Heaf JG, Ellingsen T.
PMID: 24715900
Nephron Extra. 2014 Mar 07;4(1):26-32. doi: 10.1159/000360364. eCollection 2014 Jan.

BACKGROUND: Diffuse mesangioproliferative glomerulonephritis (MesP) is the most commonly diagnosed type of glomerulonephritis (GN) in Denmark, with an incidence of 10.8 million per year. In the present study, the 30-year renal survival was estimated.METHODS: A retrospective cohort investigation of...

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Axelsen M, Smith Pedersen R, Heaf JG, et al. Mesangioproliferative glomerulonephritis: a 30-year prognosis study. Nephron Extra. 2014;4(1):26-32doi: 10.1159/000360364.
Axelsen, M., Smith Pedersen, R., Heaf, J. G., & Ellingsen, T. (2014). Mesangioproliferative glomerulonephritis: a 30-year prognosis study. Nephron extra, 4(1), 26-32. https://doi.org/10.1159/000360364
Axelsen, Mette, et al. "Mesangioproliferative glomerulonephritis: a 30-year prognosis study." Nephron extra vol. 4,1 (2014): 26-32. doi: https://doi.org/10.1159/000360364
Axelsen M, Smith Pedersen R, Heaf JG, Ellingsen T. Mesangioproliferative glomerulonephritis: a 30-year prognosis study. Nephron Extra. 2014 Mar 07;4(1):26-32. doi: 10.1159/000360364. eCollection 2014 Jan. PMID: 24715900; PMCID: PMC3977227.
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Renal evaluation in women with preeclampsia.

Nephron extra

Facca TA, Kirsztajn GM, Pereira AR, Moreira SR, Teixeira VP, Nishida SK, Sass N.
PMID: 22740065
Nephron Extra. 2012 Jan;2(1):125-32. doi: 10.1159/000338271. Epub 2012 May 22.

BACKGROUND/AIMS: Preeclampsia (PE) is a cause of glomerulopathy worldwide. Urinary retinol-binding protein (RBP) is a marker of proximal tubular dysfunction, albuminuria is an endothelial injury marker, urine protein:creatinine ratio (PCR) may have a predictive value for renal disease later...

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Facca TA, Kirsztajn GM, Pereira AR, et al. Renal evaluation in women with preeclampsia. Nephron Extra. 2012;2(1):125-32doi: 10.1159/000338271.
Facca, T. A., Kirsztajn, G. M., Pereira, A. R., Moreira, S. R., Teixeira, V. P., Nishida, S. K., & Sass, N. (2012). Renal evaluation in women with preeclampsia. Nephron extra, 2(1), 125-32. https://doi.org/10.1159/000338271
Facca, T A, et al. "Renal evaluation in women with preeclampsia." Nephron extra vol. 2,1 (2012): 125-32. doi: https://doi.org/10.1159/000338271
Facca TA, Kirsztajn GM, Pereira AR, Moreira SR, Teixeira VP, Nishida SK, Sass N. Renal evaluation in women with preeclampsia. Nephron Extra. 2012 Jan;2(1):125-32. doi: 10.1159/000338271. Epub 2012 May 22. PMID: 22740065; PMCID: PMC3383241.
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Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey.

Nephron extra

Lhotta K, Piret SE, Kramar R, Thakker RV, Sunder-Plassmann G, Kotanko P.
PMID: 22740033
Nephron Extra. 2012 Jan;2(1):147-58. doi: 10.1159/000339102. Epub 2012 Jun 01.

BACKGROUND/AIMS: Uromodulin-associated kidney disease (UAKD) is caused by uromodulin mutations and leads to end-stage renal disease. Our objective was to examine the epidemiology of UAKD.METHODS: Data from all UAKD families in Austria were collected. Patients included in the Austrian...

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Lhotta K, Piret SE, Kramar R, et al. Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey. Nephron Extra. 2012;2(1):147-58doi: 10.1159/000339102.
Lhotta, K., Piret, S. E., Kramar, R., Thakker, R. V., Sunder-Plassmann, G., & Kotanko, P. (2012). Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey. Nephron extra, 2(1), 147-58. https://doi.org/10.1159/000339102
Lhotta, Karl, et al. "Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey." Nephron extra vol. 2,1 (2012): 147-58. doi: https://doi.org/10.1159/000339102
Lhotta K, Piret SE, Kramar R, Thakker RV, Sunder-Plassmann G, Kotanko P. Epidemiology of uromodulin-associated kidney disease - results from a nation-wide survey. Nephron Extra. 2012 Jan;2(1):147-58. doi: 10.1159/000339102. Epub 2012 Jun 01. PMID: 22740033; PMCID: PMC3383240.
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ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling.

Nephron extra

Westerweel PE, Joles JA, den Ouden K, Goldschmeding R, Rookmaaker MB, Verhaar MC.
PMID: 22479264
Nephron Extra. 2012 Jan;2(1):9-16. doi: 10.1159/000335750. Epub 2012 Jan 26.

BACKGROUND/AIMS: ACE inhibitor (ACE-I) treatment effectively inhibits proteinuria and ameliorates the course of various renal diseases. In experimental glomerulonephritis, however, angiotensin II (AngII) infusion has also been shown to be renoprotective. We evaluated the long-term (28 days) course of...

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Westerweel PE, Joles JA, den Ouden K, et al. ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling. Nephron Extra. 2012;2(1):9-16doi: 10.1159/000335750.
Westerweel, P. E., Joles, J. A., den Ouden, K., Goldschmeding, R., Rookmaaker, M. B., & Verhaar, M. C. (2012). ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling. Nephron extra, 2(1), 9-16. https://doi.org/10.1159/000335750
Westerweel, Peter E, et al. "ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling." Nephron extra vol. 2,1 (2012): 9-16. doi: https://doi.org/10.1159/000335750
Westerweel PE, Joles JA, den Ouden K, Goldschmeding R, Rookmaaker MB, Verhaar MC. ACE Inhibition in Anti-Thy1 Glomerulonephritis Limits Proteinuria but Does Not Improve Renal Function and Structural Remodeling. Nephron Extra. 2012 Jan;2(1):9-16. doi: 10.1159/000335750. Epub 2012 Jan 26. PMID: 22479264; PMCID: PMC3318936.
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